A review: the Duffy blood group system

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The Duffy blood group system: a review.

Duffy was the first blood group mapped to an autosome (chromosome 1) using cytogenetic studies. Duffy antigens are located on a glycoprotein that can be found on erythrocytes and other cells throughout the body. Fy(a) and Fy(b) are products of their respective alleles (FY*A, FY*B). Fy(x) characterized by weak Fy(b) expression, is a result of an additional mutation in FY*B. The Fy(a-b-) phenotyp...

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A New Human Duffy Blood Group Specificity

The Duffy blood group system of human erythrocytes comprises a membrane glycoprotein recently characterized by immunoprecipitation techniques (1) . It is a polymorphic system that includes determinants for five alloantigens, two of which are Mendelian alleles (Fya and Fyb) (2, 3) . A null genotype, designated Fy(ab-) (4), lacks the expression of both Fya and Fyb, and is inherited as a third all...

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The LW blood group system: a review.

The Rh blood group system is one of the most polymorphic and immunogenic systems known in humans. In the past decade, intense investigation has yielded considerable knowledge of the molecular background of this system. The genes encoding 2 distinct Rh proteins that carry C or c together with either E or e antigens, and the D antigen, have been cloned, and the molecular bases of many of the anti...

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Duffy Blood Group Genotyping in Thai Blood Donors

BACKGROUND Duffy (FY) blood group genotyping is important in transfusion medicine because Duffy alloantibodies are associated with delayed hemolytic transfusion reactions and hemolytic disease of the fetus and newborn. In this study, FY allele frequencies in Thai blood donors were determined by in-house PCR with sequence-specific primers (PCR-SSP), and the probability of obtaining compatible bl...

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ژورنال

عنوان ژورنال: Immunohematology

سال: 2020

ISSN: 0894-203X,1930-3955

DOI: 10.21307/immunohematology-2019-1064